Maintenance & Support


Service is an investment in reliable equipment, a reliable process and about providing advice to the customer to help improve efficiency. Together with Applikon, we can make the difference to your process.

Service and Support

We are the certified service provider of Applikon Biotechnology in Switzerland! Here you find an overview of all our services. 

Preventive Maintenance

Applikon equipment is manufactured to the highest standards using carefully selected quality components. To ensure a long, trouble free life of your bioreactor, we recommend a regular annual service check as a preventive rather than any corrective procedure. 


Furthermore, Applikon and Resea Biotec are happy to extend our warranty when we are sure your new equipment is well maintained by an Applikon factory trained service technician. 


With the preventive maintenance contract we guarantee to respond on customer service requests within 24 hours. 


We put together some frequent asked questions, which might help you in with handling your Applikon controller and bioreactor. This collection of FAQs will be kept up to date. Let us know, if you are missing some questions. 

The heater tank of a Thermo Circulator contains a float as water detector. In case of an empty heater tank, an error message will be presented and the heating element will be disabled.


The heater tank must be filled with water before the actuator can be put to use. This screen can be opened using the following navigation path: 



Press “fill” the button in the Additional Configuration section of the screen. As soon as the Thermo Circulator is filled with water (warning sign in the Menu button will disappear and water will flow to the drain), press the “stop filling” button. Then press the “Activate” button. 

The Stirrer Speed Controller (that is a control loop itself) can be used as actuator that is assigned to the dO2 Control Loop (an increasing stirrer speed will result in a better dispersion of the gas bubbles in the medium). In that case, the lower and upper limit of the stirrer speed can be set using the so called Cascade Limits.


The Cascade Limits are presented in the Stirrer Settings > Limits screen (indicated by a red rectangle in the adjacent image).
When the stirrer speed controller is used as (manual) stand-alone control loop, the Cascade Limits are disabled.


When mounting the head plate on top of the reactor, make sure to fix the mill nuts / slotted nuts in a crosswise manner! Please dont use any tools to fix the screws of the bioreactor – your WoMan power is sufficient!

  • P-gain:
    Proportional gain; causes a controller output that is proportional to the deviation
  • I-interval
    Integrates the deviation to correct for a systematic offset
  • D-interval
    Evaluates the trend and prevents a large overshoot
  • Dead Band
    Prevents excessive actuator actions when setpoint is reached
  • Cycle Time
    Defines the Control Loop refresh time

During the cultivation, the Sample Correction procedure is used to correct the on-line measured pH value with data from off-line pH measurements in samples. Only the current offset is corrected by entering the off-line measured value 


Press the “sample correction” button and use the presented numeric keypad to enter the pH value that was measured in the sample. The measured value will be corrected and the difference between on-line value and corrected value is presented in the calibration screen.

The control software is able to detect a “Low Gas Flow” occurrence and will generate an alarm. 

  • When the actual measured gas flow is smaller than 50% of the required gas flow, the Low Flow alarm is triggered. In an attempt to cure the problem, the software will retry to open the block valve (max. 5 times).
  • If the issue is not resolved automatically, pleaes get in contact with us. Often, the gas inlet flow is to low. the magnetic valve doesn’t open properly  or the valve is not properly aligned with the MFC. 

The dO2 measurement is based on the polarographic principle (Clark-cell). Therefore, the sensor must be polarized for at least 4 hours before it can be calibrated. If the sensor is calibrated before polarizing, the measurement value can differ from the actual value in the vessel. 

Get your support!

We look forward to providing you with fast, reliable and good service at all times. 


We are happy to work with you on a service contract based on your needs. We look forward to your enquiry.  


System and operation manuals: 

Please contact us, and we will provide you the right manual for your system!

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