ez2-Control bundle

Our Applikon BioBundles are complete bioreactor systems with everything you need for successful cultivation. 

The turnkey solutions consisting of a controller and a bioreactor include silicone tubing, sample bottles, a spares kit, and Applikon’s data acquisition software, Lucullus Lite. 

The bioreactors come in a wide range of volumes: 2L, 3L, 5L, 7L, 15L, and 20L, and they are perfect for cell and microbial cultures. The control system for these small-scale bioreactors is the Applikon ez2-Control

Customize your bioreactor system with one or more of our add-on packs.

Features

  • Quality without compromise: we use the highest quality materials.
  • Ease of use and sophistication in one BioBundle.
  • Our solutions are configurable and customizable.
  • Get peace of mind with 1 Applikon ez2-Control per bioreactor.
  • Acquire data with the included software.
  • Save costs and time with standardization.

Efficiently Optimized

Applikon bioreactor systems are designed to meet your needs with the utmost reliability and accuracy. Everything is manufactured to operate efficiently, and no detail is overlooked.

  • A quiet agitation motor is included.
  • Smooth stainless steel contact surfaces avoid cross-contamination.
  • The ez2-Control has a sophisticated but straightforward integrated touch screen.
  • Software updates are easily performed through USB without an external Service Engineer.
ez2-Control

Specifications of ez2-Control bundles

Our standard setups are highly sophisticated and can be adapted  based on your application. The cell culture and microbial fermentation bundles share many of its components.  Nevertheless, there are some differences between the bundles which can be further customized to meet your specific needs.

Cell Culture
Microbial
Agitator
Lipseal or magnetic with Marine impeller
Lipseal or magnetic with Rushton impellers
Aeration
Air and Oxygen supply via sparger
Air and Oxygen supply via sparger and overlay
pH
Control via liquid alkali pump and CO2 gas supply
Control via liquid alkali and acid addition pump
Temperature
Heating via heating blanket, Peltier optional
Heating via heating blanket, cooling by cold water in heat exchanger
Dissolved Oxygen
Control via Air and O2 gas supply
Control via Air and O2 gas supply and agitation speed
Foam
Optional
Control via anti-foam addition pump
Liquid additions
3 ports in triple inlet and one inoculum port
3 ports in triple inlet, one inoculum port and one septum port
One liquid addition bottle included
Two liquid addition bottles included
Single and jacketed wall
Total Volume2 L, 3 L, 5 L, 7 L, 15 L, 20 L
Working Volume1.7 L, 2.7 L, 3.4 L, 5.4 L, 12 L, 16 L
Drive systemDirect drive, lip sealed or magnetically coupled
Stirrer speed (rpm)Standard range is 50 – 1250
 2 and 3 liter systems can be supplied with 2000 rpm motor
ImpellersRushton and marine with outside diameters 45 mm,
60 mm 75 mm or 85 mm
Gas spargerPorous sparger or L-type sparger
Gas overlayYes
Exhaust gasWater cooled exhaust gas condenser
SamplingFixed height or height adjustable sample pipe with optional sampling system
 Sample pipe internal diameters choices are: 1.7 mm, 4 mm, 6 mm or 10 mm
DrainingDrain pipe
AdditionsTriple or single inlet ports and optional micro liquid injectors
Optional inletsSeptum, chemostat tube, liquid entry system
pHMeasurement: 12 mm classic pH sensor
Control: via acid pump or CO2 gas (rotameter or MFC) in combination with alkali pump
DO2Measurement: 12 mm classic polarographic DO2 sensor or LumiSens for 2-5 L
Control: via a combination of N2, Air, O2 (Rotameter or MFC) and agitation
TemperatureMeasurement: Pt-100 sensor in thermowell in topplate
Control: cooling and/or heating jacket via bioreactor wall or via internal heat exchanger
FoamMeasurement: Height adjustable conductivity based foam sensor
Control: anti-foam addition pump
LevelMeasurement: Height adjustable conductivity based level sensor
Control: pump for liquid addition or removal
Optional sensorsBiomass, Optical Density, O2 and CO2 off gas, weight balance

Lucullus Lite is included with all BioBundles. 

Other software solutions like Standard/Advanced or Expert versions of Lucullus or the BioXpert W10 software can alternatively be supplied with the system. 

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Facts and Figures

Applications:

  • Yeast
  • Cultivation of microorganisms
  • Cultivation of mammalian cells
  • Suspension cells
  • Adherent cells on microcarriers
  • Continuous perfusion cultures
  • Plant cell cultures
  • Algae
  • Fungi

 

Volumes

2, 3, 5, 7, 15 and 20 liter total volume

(single- and jacketed version available)

 

More information: 

In future, the new Livit Flex controller will replace the ez2Control.

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Applikon ez2-Control bundle

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